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Science Version

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  1. Introduction

  2. Chronic inflammation (CI) - the basis of “all” diseases

  3. Stress as the cause of “all” immune responses

  4. Bias of the female immune system versus that of the male

  5. The innate (aka “natural”) immune system and immunity

  6. Evolutionary development of the immune system (Part 1)

  7. Evolutionary development of the immune system (Part 2)

  8. Embryology and pregnancy related to the immune system

  9. The adaptive (aka “acquired”) immune system: from friend to foe

  10. Immunogenetics and Immunogenomics

  11. The Human Genome Project (HGP), Precision (personalized) medicine and “All of Us” (Value of Artificial intelligence [AI], machine learning and big data analytics in immunology)

  12. XCI (lyonization)

  13. The microbiome

  14. Chronic inflammation (CI): “Enemy #1” (Part 1: Etiologies)

  15. Chronic inflammation (CI): “Enemy #1” (Part 2: Pharmacology and pharmacodynamics)

  16. Chronic inflammation (CI): “Enemy #1” (Part 3: A multisystem pathology)

  17. Neuroimmunology

  18. Autoimmune disease: When self becomes the villain (Part 1: Etiologies)

  19. Autoimmune disease: When self becomes the villain (Part 2: Female bias)

  20. Autoimmune disease: When self becomes the villain (Part 3: Clinical considerations)

  21. Immunotherapeutics (Monoclonal antibodies and biologics) (741 words)

  22. Immunotherapeutics (cellular and genetic) procedures (Part 1: Stem cell transplantation therapy [regenerative medicine])

  23. Immunotherapeutics (cellular and genetic) procedures (Part 2: Homograph [allograph] transplantation)

  24. Immunotherapeutics (cellular and genetic) procedures: (Part 3: Genetic engineering/modifications)

  25. Immunotherapeutics (cellular and genetic) procedures (Part 4: CAR-T and CAAR-T cell [gene replacement] therapy)

  26. Immunotherapeutic (cellular and genetic) procedures (Part 5: CRISPR-Cas9 [gene editing] therapy)

  27. Cancer: Immunology’s cruelest enemy and greatest challenge (Part 1: Epidemiology)

  28. Cancer: Immunology’s cruelest enemy and greatest challenge (Part 2: Etiologies)

  29. Cancer: Immunology’s cruelest enemy and greatest challenge (Part 3: Microbiome, XCI and microRNA)

  30. Cancer: Immunology’s cruelest enemy and greatest challenge (Part 4: Clinical considerations and diagnosis)

  31. Cancer: Current treatment considerations (Part 1: Chemotherapy, Radiation therapy and Molecular targeted therapy)

  32. Cancer: Current treatment considerations (Part 2: Immunotherapeutics, Cellular and genetic procedures)

  33. Cancer: Current treatment considerations (Part 3: Idiotype-anti-idiotype Regulatory Circuit [or Loop])

  34. Cancer: Current treatment considerations (Part 4: Combination strategies in cancer immunotherapy)

  35. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 1: Immunopathogenesis and Sars-CoV-2 life cycle)

  36. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 2: Natural pathogenesis and genetic and genomic considerations)

  37. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 3: Clinical considerations)

  38. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 4: Treatment and management strategies: General measures)

  39. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 5: Treatment and management strategies: Immunotherapies)

  40. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 6: Treatment and management strategies: Anti-viral drugs)

  41. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 7: Treatment and management strategies: Vaccines) (548 words)

  42. Immunology’s role in pandemics, infectious disease and COVID-19 (Part 8: Vaccination [immunization]) (545 words)

  43. Immunology’s role in Immunoinformatics (computational immunology) and epidemiological considerations in COVID-19

  44. Immunology’s role in public health considerations and recommendations

  45. Epilogue

SCIENCE VERSION

Full scientific terminology

with expert discussion

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LAYPERSON VERSION

Lay audience version with limited scientific terminology and informal discussion

​

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